No the journals aren't the "end-all be-all", successful experience with the supplements is. And if the scientific-recommended supplements were working, why stop?
Don't get me started on the sheer volume of well-performed, "comprehensive" studies that have been completed. If you would like I can do some work over the next weekend and post a very long post full of such information for you to play with over creatine, glutamine, BCAA's, protein and carbs after exercise versus 3 hours later, association between insulin and increased protein synthesis, comparing water, sports drink, protein drink alone, carbohydrate with protein drink, and placebo.
You show very little respect for scientists. Did you ever think why many of studies have to involve a low number of participants? That's because they have to control their lives; their eating habits, when they exercise, which exercise they do, they all have to be the same. In many cases, those who submitted themselves to the study are under constant supervision which throws your human nature argument out the window. Some of the United States best scientists have done these things. Unbiasedness is their forte.
While their "child's play" as you called it to critique at least the scientists are trying to do something constructive. How do you suggest scientists match subjects up by genetic material? Seeing as everyone's genetics are COMPLETELY different than every other. Even those in the same immediate family can respond differently to exercise due to gene differences in muscle fiber count (and type) and hormone levels. Is what you are suggesting to include people of the same body type? Everyone has different percentages of ectomorphism or mesomorphism anyhow. In the end, human beings are different, but they're very much the same as well. And when you get remarkable results from one concoction with many different people (with differing genetics) compared to placebo, which the volunteers also possibly assumed was the experimental potion, you had a result with that study!
And you're talking to a scientist, so I'm very aware how much money it costs to fund a study. I can tell you this is the main reason sport's physiologists keep the studies down to only 5-10 peopls most times, the other reason being to have enough manpower to observe them around the clock many times.
You said:
"I also admit to an undying suspicion directed to studies done by the supplement companies. Yes, supposedly a third party is often hired to do the study and provide the results, and I'm sure there are reputable ones out there. But in the end, who's the client? Who's paying the bills? "
That is a completely different ballpark. Most legitimate supplement companies quote previously-done studies rather than the one's they asked to be completed. However, most supplement companies are not legitimate! :) So there you have it. You won't get any argument from me. That's why I suggest reading journals and college department websites as opposed to supplement company ads.
"Having said that, a meta-analysis of many small studies, however flawed, can suggest that some suppements are more likely than not to have a beneficial effect without causing harm. If they are otherwise harmless, then there is no reason to not take them."
I'm a bottom line kind of guy, and that is the bottom line. Not only will it likely not cause harm, but you can be quite sure if the study was published with a result that you will receive a benefit.
<message edited by ShaqAtack on Wednesday, March 22, 2006 8:37 AM>