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Transdermal or Oral?

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Transdermal or Oral? - 6/14/2003 9:30:00 AM

Marc David

Posts: 9184
Joined: 4/6/2003
From: Bay Area -CA
Status: offline

I' ve checked out a few supps on Supplements101 in regards to Pro-Hormones.

Not knowing anything about them..

I' ve seen various products in both an oral form and transdermal?

Can somebody just explain the terms to me (I' m guessing one is taken via the mouth Smile

and one is applied to an area on the skin).

Just not sure which method works better and why would skin be any better then taking a pill?

Thanks

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RE: Transdermal or Oral? - 6/15/2003 8:55:44 AM 1 votes

Robboe

Posts: 908
Joined: 6/9/2003
From: Newcastle, UK
Status: offline

Twin Peak will ellaborate a lot more than me, but here' s the gist:

1. A lot of compounds have poor bioavailability - that is, you eat them, the liver ****s them and renders them mostly useless, and then you piss them out.

2. By going topically/transdermally, you can get the compound through the skin straight into the bloodstream, avoiding the liver almost completely. Thus, you get more of the compound doing the job.

This is idea for some prohormones like 4diol (ace transdermal, not so ace oral). However, compounds like 1,4 andro actually has good oral bioavailability, so you can take it either way and get good blood concentrations.

(in reply to Marc David)

Post #: 2