Fat cells shrink from exercise in abdominal's

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Fat cells shrink from exercise in abdominal's - Thursday, August 17, 2006 10:05 AM ( #1 )
I found this article this morning, and went directly to the reasearch page to see what it was about, basically this is yet another study showing that if you truely want to trim down, diet alone is not as effective as diet and training... now this was a study for females, but I would assume that the same would go for men as well. One question that I have about this, is that is the additional caloretic deficit from the training the reason for the cell shrinkage?

Here is the link, pretty interesting http://www.nature.com/ijo/journal/v30/n8/abs/0803245a.html

Looking at some other blogs they also have some interesting views of this.

Objective: 
To determine if hypocaloric diet, diet plus low-intensity exercise, and diet plus high-intensity exercise differentially influence subcutaneous abdominal and gluteal adipocyte size in obese individuals.



Design: 
Longitudinal intervention study of hypocaloric diet, diet plus low-intensity exercise, and diet plus high-intensity exercise (calorie deficit=2800 kcal/week, 20 weeks).



Subjects: 
Forty-five obese, middle-aged women (BMI=33.00.6 kg/m2, age=581 years).



Measurements: 
Body composition testing and adipose tissue biopsies were conducted before and after the interventions. Subcutaneous abdominal and gluteal adipocyte size was determined.



Results: 
All three interventions reduced body weight, fat mass, percent fat, and waist and hip girths to a similar degree. Diet only did not change subcutaneous abdominal adipocyte size, whereas both diet plus exercise groups significantly reduced abdominal adipocyte size. Changes in abdominal adipocyte size in the diet plus exercise groups were significantly different from that of the diet group. Gluteal adipocyte size decreased similarly in all three groups.



Conclusion: 
Addition of exercise training to dietary weight loss preferentially reduces subcutaneous abdominal adipocyte size in obese women. This may be of importance for the treatment of health complications associated with subcutaneous abdominal adiposity
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RE: Fat cells shrink from exercise in abdominal's - Thursday, August 17, 2006 10:51 AM ( #2 )

One question that I have about this, is that is the additional caloretic deficit from the training the reason for the cell shrinkage?

 
Referring to:
Diet only did not change subcutaneous abdominal adipocyte size, whereas both diet plus exercise groups significantly reduced abdominal adipocyte size.
 
Remember that these are all obese people.
In obese people, fat behaves differently than in someone with a moderate or low bodyfat, so that is a factor.
 
Naturally we would expect to see a larger loss of fat mass with the exercising group and, if they used resistance training, an increase of lean mass, which could result in a lower overall loss of weight but a greater loss of fat mass. 
 
Now with the exercising group vs the non exercising group:
 
In previous studies we have seen that usning only a hypocaloric diet (calorie defiecient) leads to a loss of total weight from fat and lean mass.
 
Addition of aerobic exercise only to the hypocaloric diet led to a slightly higher overall weight loss, again from fat and lean mass.
 
Addition of resistance training led to a sparing and even increase of lean mass while increasing the amount of total fat mass lost.
 
Adding exercise could also deminish overall stress and cortisol, which could lesson the amount of stress related fat storage which deposited in the abdominal region.
 
There are additional hormone and neurotransmitter actions which might contribute to the overall effect of minimizing deposition of fat in the abdominal area.
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RE: Fat cells shrink from exercise in abdominal's - Thursday, August 17, 2006 10:56 AM ( #3 )
What is interesting in this, is that they do not really talk about resistance training, it really seems to be talking more aerobic. Is it possible that there is a hormone response to the exercise which causes the cells to shirnk in size? If so, how would you trigger the same response in other areas of your body?
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RE: Fat cells shrink from exercise in abdominal's - Thursday, August 17, 2006 11:40 AM ( #4 )

Is it possible that there is a hormone response to the exercise which causes the cells to shirnk in size?  If so, how would you trigger the same response in other areas of your body?


I think you may have missed the point....it was not only that they shrunk...in all cases they probably did shrink all over and then - in the diet only they re-deposited the fat...but in the exercise group they shrunk and did not re-deposit fat in the abdominal region as in the diet only. 
 
Remember that with a hypocaloric diet there is some stress pecieved by the body...which could lead to the absence of measured shrinkage in the diet only group. (remember measures were only take before the start and at the end...and these cells expand and contract constantly.)
 
Also note that these are women and are more likely to store fat in the gluteal area than in the abdominal area...only these two areas were measured.  So we don't know what changes happened elsewhere.
 
In men we might have seen a reverse in this.  More fat cell shrinkage in the gluteal area.
 

What is interesting in this, is that they do not really talk about resistance training

Witout looking at the whole report we don't see what type of exercise the people did.  Though, the full details are given in the experimental design description.
 
To answer, you can not target fat loss specifically..beyond your genetic predisposition.

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